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FAQs
1 The Pancreas
2 Pancreatic Cancer
3 Causes of PC
4 Heredity
5 Risk Factors
6 Diagnosis
7 Metastasis
8 Staging
9 Questions to ask
10 Surgical Treatment
11 Medical Treatment
12 Vaccine
13 Symptoms & Side Effects
14 Screening
15 Pain Management
16 Diet & Exercise
17 Final Stages & Hospice


5) What are risk factors for pancreatic cancer?

There are some factors which can increase the risk of acquiring the genetic mutations that may potentially result in pancreatic cancer. These risk factors are outlined in the table below. You will notice that coffee and alcohol are not listed. Currently there is not strong evidence to suggest that consumption of either substance will increase your risk for developing cancer of the pancreas.


Known Risk Factors
1) Cigarette smoking Cigarette smoke contains a large number of carcinogens (cancer causing chemicals). Therefore, it is not surprising that cigarette smoking is one of the biggest risk factors for developing pancreatic cancer. For example, smoking during college has been associated with a 2-3 fold increased risk of pancreatic cancer.
2) Age The risk of developing pancreatic cancer increases with age. Over 80% of the cases develop between the ages of 60 and 80.
3) Race Studies in the United States have shown that pancreatic cancer is more common in the African-American population than it is in the white population. Some of this increased risk may be due to socioeconomic factors and to cigarette smoking.
4) Gender Cancer of the pancreas is more common in men than in women. This may be, in part, because men are more likely to smoke than women.
5) Religious Background Pancreatic cancer is proportionally more common in Jews than the rest of the population. This may be because of a particular inherited mutation in the breast cancer gene (BRCA2) which runs in some Jewish families.
6) Chronic pancreatitis Long-term inflammation of the pancreas (pancreatitis) has been linked to cancer of the pancreas. The reason for this association is not clear, but it is greatest in patients with inherited chronic pancreatitis.
7) Diabetes There have been a number of reports which have suggested that diabetics have an increased risk of developing pancreatic cancer. The reasons for this are not clear.
8) Peptic ulcer surgery Patients who have had a portion of their stomach removed (partial gastrectomy) appear to have an increased risk for developing pancreatic cancer.
9) Diet Diets high in meats, cholesterol fried foods and nitrosamines may increase the risk, while diets high in fruits and vegetables may reduce the risk of pancreatic cancer.




     
 

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Disclaimer: No two patients with pancreas cancer are identical. The appropriate treatment of individual patients with pancreatic cancer varies greatly depending on the patient's medical and surgical history. The information expressed in this Web page is not medical advice. It is meant only to educate health care professionals and patients about the current status of treatment and research in pancreas cancer at Hopkins. Before making any medical decisions, patients with pancreatic cancer are advised to consult with their personal physicians.