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Steven D. Leach is the Paul K. Neumann Professor in Pancreatic Cancer, Chief of the Division of Surgical Oncology, and Director of Research in the Department of Surgery at Johns Hopkins. Dr. Leach received his undergraduate degree in
Biology at Princeton University, followed by his M.D. degree at Emory. He subsequently completed training in Surgery and Cell Biology at Yale, as well as a fellowship in Surgical Oncology at the University of Texas M.D. Anderson Cancer Center. Dr. Leach directs an NIH-funded research program focused on epithelial differentiation in exocrine pancreas, using both mouse and zebrafish model systems. This work is based on the general hypothesis that pancreatic cancer may be initiated by characteristic changes in epithelial differentiation. By elucidating the molecular mechanisms regulating exocrine differentiation in developing pancreas, Dr. Leach's lab has provided important new insights regarding abnormal differentiation events occurring during pancreatic tumorigenesis. His work has demonstrated critical links between early forms of pancreatic cancer and the epithelium of the embryonic pancreas, providing exciting new strategies for disease detection and chemoprevention.Dr. Leach recently joined the Johns Hopkins Departments of Surgery and Oncology as the first Paul K. Neumann Professor in Pancreatic Cancer.
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