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GENERAL SUPPORT
The treatment of cancer is undergoing a radical change. In the future, patients will no longer receive "generic" chemotherapy, but rather therapy that is specifically tailored to their tumor. This will require the application of sensitive new molecular tools to traditional biopsy methods, such as those used by cytopathologists.

We strongly believe that the application of molecular techniques to cytologic biopsy samples will vastly improve the detection and treatment of cancer in the future. But these new technologies require resources above and beyond those we've already dedicated to this research. Financial support is needed to develop creative new approaches to cancer diagnosis, including breast cancer, lung cancer, liver cancer, melanoma, and cervical cancer.

Individuals may give direct donations, leave money as a bequeath, or ask that donations be sent in lieu of flowers. Those of you wishing to support Cytopathology research at Johns Hopkins may do so by sending your tax-deductible contribution payable to the Johns Hopkins University to:

Douglas P. Clark, M.D.
Department of Pathology
The Johns Hopkins Hospital
406 Pathology Bldg.
600 N. Wolfe St.
Baltimore, MD 21287

If you have any questions about how you can help support our research efforts in Cytopathology, do not hesitate to call Dr. Clark at 410-955-1180.


IN LIEU OF FLOWERS

We have received a number of donations in lieu of flowers. This is a wonderful way to both honor a loved one and to help fight this terrible disease. These donations are made at very difficult times, and we therefore wanted to simplify the process. If you have lost a loved one and would like donations sent to Hopkins to help battle this disease in lieu of flowers, all you need to do is:

A. Ask the donor to:
  1. Make donations payable to: "Johns Hopkins University."

  2. Indicate on the memo line of the check the name of the individual in whose memory the donation is being made.

  3. Mail the donation to:
      Douglas P. Clark, M.D.
      Department of Pathology
      The Johns Hopkins Hospital
      406 Pathology Bldg.
      600 N. Wolfe St.
      Baltimore, MD 21287
B. Please include with your donation the name and address of where you would like acknowledgments to be sent (or you may call our office 410-955-9132) .

When we receive memorial donations, we send a thank you to the donor and we also send a complete list of the names and address of the donors to the relative of the deceased.

We realize that the death of a loved one is extremely difficult. We hope these simplified instructions will help those of you who wish to honor your loved one with bequests to Johns Hopkins for Cytopathology research.




CREATING A NAMED ENDOWMENT FOR CYTOPATHOLOGY RESEARCH

Research requires money, and although most of the support for medical research comes from the federal government via the National Institutes of Health (NIH), it is private philanthropy that can provide the margin of excellence to a research enterprise. Private funds are flexible and can be deployed quickly to take advantage of new ideas and new people. Private funds also can form a constant base for faculty support upon which grant support can be superimposed. Private funds are particularly needed to support research on Cytopathology. This is because Cytopathology research is woefully underfunded by the NIH. There have been several examples of private giving having a significant impact on a cancer. For example, the Clayton Fund in Basic Colon Cancer Research has laid the foundation for the remarkable success of the colon cancer research team here at Hopkins. Thanks to the Clayton Fund, many of the most significant discoveries in cancer biology in the last decade were made by the colon cancer team at Johns Hopkins (Bert Vogelstein who leads this team is now the most cited scientist in all of science).

Endowments are wonderful ways to honor a loved one — they are named and they are permanent. Once established, the principal of the endowment is invested by the University. A portion of the income generated each year is reinvested to insure the long-term growth of the Fund. The remainder of the income generated is given to the scientists to support their research.

(Endowments start at $20,000. If they reach the $100,000 level a plaque is placed in the research labs honoring the donor. If they reach the $5-10 million level, then the endowment can be used to name a research center).


ENDOWED CHAIR FOR CYTOPATHOLOGY RESEARCH

"Everything that is really great and inspiring is created by the individual who can labor in freedom"
Albert Einstein

The establishment of an endowed chair for Cytopathology Research at Johns Hopkins would create a stable, leadership position in an exciting new area of cancer research. Cancer treatment is becoming more individualized, as new targeted therapies emerge. But this will require sophisticated new biopsy techniques to determine which patients are eligible for each new therapy. This endowed chair would permit huge advances in this area, rapidly bringing together new technologies with traditional biopsy methods. Because endowed chairs are permanent, named chairs are a wonderful way of permanently honoring the donor.

The cost for a named endowed chair is approximately $2.0 million.


ENDOWED FELLOWSHIP TRAINING PROGRAM: New Technologies in Cytopathology Research

Please help us to celebrate the achievements of our mentor, colleague, and friend through supporting the fellowship in his honor.

Dr. Yener Erozan's love of teaching is embodied in his prolific publications. During a distinguished career, which has spanned more than 40 years, Dr. Erozan has generated over 90 peer-reviewed articles, 13 non-peer reviewed articles, 14 book chapters, 2 books and a variety of multi-media teaching materials. In addition, he continues to be involved in numerous classrooms, national and international CME instructional activities. The continued success of the world-renown Postgraduate Institute for Pathologists in Clinical Cytopathology established by Dr. John K. Frost is a testament to his leadership. Today he continues to be involved in the Division's abbreviated "Institute" as Director Emeritus. In addition to his significant contributions as an educator, Yener Erozan has embraced clinical and research technologies that have significantly impacted the practice of Cytopathology. Dr. Erozan has been a leader in the area of fine needle aspiration, one of the major new areas in Cytopathology in the last twenty-five years. His research interest in pulmonary pathology has involved the application of molecular probes to cytologic specimens. His papers have been published in significant journals of his specialty and he has been an Associate Editor for Acta Cytologica since 1992. [more about Dr. Erozan]

So much of his career has been dedicated to teaching it seems only fitting that we create this fellowship to honor him. Endowing a training program in Cytopathology at Johns Hopkins will perpetuate Yener Erozan's legacy.

Endowment generated income will make an enduring difference in the lives of our Cytopathology fellows and help to secure the future of our training programs. The Yener S. Erozan Fellowship in Cytopathology emphasizes the diagnostic, teaching and clinical research activities that are his life. Please join us as we celebrate the achievements of our mentor, colleague, and friend by supporting the fellowship in his honor.

BUDGET
1 Fellow (1 year X $50,000/year)$50,000
1 Fellow (2 years X $50,000/year) $100,000 (most Fellowships last 2 years)
Permanent Endowed Fellowship $750,000

WHAT YOUR DONATION BUYS

One human gene contained within a cloning vector $10

Membranes for screening new genes $15

Reagents needed to isolate DNA from a patients' blood sample $20

A pair of PCR primers used to amplify one gene $30

Bacterial clone containing tumor-related gene $30

Vials for freezing tumor samples $35

Enzyme to precisely cut DNA $40

Scalpel blades for dissection of tumor samples $55

Enzyme to join DNA fragments $60

Updates to lab manual $70

Flasks for growing tumor cells $75

Radiolabel used to label DNA for sequencing and probing $100

Tumor cell line $100

Gel mix used to resolve DNA on gels $100

A vial of enzyme to modify or amplify DNA $100

Serum to grow cancer cells $130

DNA purification kit $150

Reagents to introduce genes into cancer cells $180

Purification kit for tumor-suppressor proteins $230

X-ray film to detect DNA sequence of a gene $270

Plates for drug-screening reactions $380

Enzyme to amplify DNA from tumors $400

DNA fragments to study a new gene $500

Lab refrigerator used in ongoing experiments $700

Digital camera for web page construction/updates $800

Set of pipettes to measure chemical solutions $900

Lab computer to access gene database $1,800

Ultraviolet light and camera to visualize DNA $2,000

Incubator for tumor cell culture $2,700

Set of DNA sequencing apparatus $3,800

Lab freezer $5,000

Centrifuge for drug screens and purifications $7,000

PCR machine to amplify DNA $9,000

Named permanent endowment $10,000 and up

Drier for DNA gels and purifications $12,000

Cancer Research Technician $30,000/yr

Drug library to screen for new therapeutics (19,000 drugs) $38,000

Research fellow and supplies $50,000/yr

Named permanent endowed research fellowship $750,000

Named permanent endowed chair for Cytopathology research $2 million

Named endowed Cytopathology center $5 million

Named University $1 billion

[Cytopathology Home]


Division of Cytopathology
Webmaster: Douglas Clark, M.D.
dclark@jhmi.edu
Johns Hopkins School of Medicine
Last updated: January 16, 2002

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