| Email |
pburger@jhmi.edu |
| Phone |
(410) 955-8378 |
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Peter C. Burger , M.D.
Primary Appointment in Pathology; Secondary Appointments in Neurosurgery, Oncology
My principal interest is in surgical neuropathology of both neoplastic and non-neoplastic diseases. For both, I am seeking the best methods by which these lesions can be diagnosed, and their biological behavior projected. Our current work explores molecular basis of gliomas, specifically molecular or cytogenetic abnormalities that correlate with tumor type and prognosis. We are involved in a multi-institutional study of the pathological cytogenetic, and molecular features of gliomas, particularly those that can be used to distinguish oligodendrogliomas from histologically similar lesions such as astrocytoma. We are also categorizing the cytogenetic and molecular features of pediatric astrocytomas and to subdivide medulloblastomas on the basis of their cytogenetic and molecular anatomy. With joint appointments in Oncology and Neurosurgery, I work closely with these disciplines in the evaluation of new therapies for CNS tumors. We have an active consult service for the interpretation of surgical specimens for brain and spinal cord tumors and other lesions.
Publications
Burger, P.C., Minn, A.Y., Smith, J.S., Borell, T.J., Jedlicka, A.E., Huntley,B.K., Goldthwaite, P.T., Jenkins, R.B., and Feuerstein, B.G.: Losses of Chromosomal Arms 1p and 19q in the Diagnosis of Oligodendroglioma. A Study of Paraffin-Embedded Sections. Modern Pathology 14:842-853, 2001.
Burger, P.C., Pearl, D.K., Aldape, K., Yates, A.J., Scheithauer, B.W.,Passe, S.M., Jenkins, R.B., and James, C.D. Small Cell Architecture - Ahistological Equivalent of EGFR Amplification in Glioblastoma Multiforme? J.Neuropathol. Exp. Neurol. 60:1099-1104, 2001.
Eberhart, C.G., Kratz, J.E., Schuster, A., Goldthwaite, P., Cohen, K.J.,Perlman, E.J., and Burger, P.C.: Comparative Genomic Hybridization Detects an Increased Number of Chromosomal Alterations in Large Cell/Anaplastic Medulloblastomas. Brain Pathology 121:36-44, 2001.
Eberhart, C.G., Kepner, J.L., Goldthwaite, P.T., Kun, L.E., Duffner, P.K.,Friedman, H.S., Strother, D.R., and Burger, P.C.: Histopathologic Grading of Medulloblastomas: A Pediatric Oncology Group Study. Cancer 94:552-560,2002. |
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