AssayPage

	Clinical Background	Clinical Utility	Assay Principle	Results	Sample Requirements	Case Tutorial	References
	Written by: Karin Berg, M.D.

Clinical Background:

Identification of clonal rearrangements of the IgH gene supports the diagnosis of a lymphocytic malignancy, in an appropriate clinical and pathologic setting.

The detection of clonal B-cell populations is not, by itself, necessarily diagnostic of a B-cell malignancy.

Frequently, clonality assays are used on otherwise equivocal diagnostic cases.

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