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  Written by: Alexandra Valsamakis, M.D., Ph.D.


Clinical Background: The human polyomavirus BK virus (BKV) is ubiquitous and infects a high proportion of the population. Primary infection occurs during childhood and is usually not apparent but may be accompanied by mild respiratory illness. During primary infection, there is viremia and the virus is transported to the kidney, where it persists indefinitely. Immunocompromised conditions result in reactivation of virus and viruria. Polyomavirus viruria has been documented most extensively in recipients of renal allografts, bone marrrow transplant patients, and in pregnant women.  









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