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Pancreas Cancer Research* |
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When we receive memorial donations, we send a thank you to the donor and we also send a complete list of the names and address of the donors to the relative of the deceased.
We realize that the death of a loved one is extremely difficult. We hope these simplified instructions will help those of you who wish to honor your loved one with bequests to Johns Hopkins for pancreas cancer research.
Just as the Clayton Fund has had an impact on our understanding of colon cancer, so too would the establishment of a Fund for pancreatic cancer research have a fundamental impact on the fight against pancreatic cancer.
Endowments are wonderful ways to honor a loved one. Once established, the principal of the endowment is invested by the University. A portion of the income generated each year is reinvested to insure the long-term growth of the Fund. The remainder of the income generated is given to the scientists to support their research.
(Endowments start at $100,000. A plaque is placed in the research labs honoring the donor. If they reach the $10 million level, then the endowment can be used to name a research center).
The establishment of an endowed chair for pancreatic cancer research would allow us to pursue high-risk research work. We believe this work will advance our understanding of pancreatic cancer, not by small steps, but instead by leaps and bounds. All to often, scientists focus their efforts on "evolutionary" work because it is safer, and more of a sure bet. Endowed chairs allow scientists such to pursue revolutionary work. In addition named chairs are a wonderful way of permanently honoring the donor.
The cost for a named endowed chair is approximately $2.3 million.
At the same time, young minds are the most creative minds. Human creativity peaks at a rather young age; as our fund of knowledge increases our creativity paradoxically decreases. Indeed, some of the major new ideas in cancer research in the last several years have come from young scientists in their training. For example, Victor Velculescu here at Johns Hopkins created the idea for the revolutionary technology of serial analysis of gene expression (SAGE). Victor did this while he was a post-doctoral student in the Johns Hopkins cancer research laboratories.
We propose to create an endowed fellowship training program in pancreatic cancer research at Hopkins. This program will provide secured funding to young scientists and physicians wishing to pursue a career in pancreatic cancer research. The research fellowship program will not be a standard fellowship program. Instead it will take advantage of and most importantly encourage the creativity of the trainees. The fellow will not be a mere technician following detailed instructions from a mentor. Instead, the fellows will be given extensive free time and the fellowship will be focused on creating novel new technologies which can be applied to cancer research and on identifying new technologies, developed in other fields, which can be applied to pancreatic cancer research.
This approach will bring more minds to the battle against pancreatic cancer. Furthermore, the focus on creative spark will mean that our understanding will advance not in safe yet small steps, but rather in daring leaps.
BUDGET
| 1 Fellow (1 year X $50,000/year) | $50,000 |
| 1 Fellow (2 years X $50,000/year) | $100,000 (most Fellowships last 2 years) |
| Endowed Fellowship | $1,700,000 |
A number of people have asked how they can make a bequest and about other forms of planned giving. Planned giving can be a wonderful way to support pancreatic cancer research. Depending on the arrangements you choose you can also:1) Reduce your income taxes,
2) Get more favorable capital gains tax treatment,
3) Increase your spendable income,
4) Retain payments for life, and
5) Achieve no-cost, worry-free asset management.
To learn more about planned giving opportunities visit http://jhu.plannedgifts.org/ways_to_give.html or contact the Planned Giving Office at Johns Hopkins:
Bernard J. Davisson II
Senior Director of Gift Planning
Phone: (410)516-7954 or (800)548-1268
Special Fundraisers
There have been special events organized by family members of those afflicted with pancreas cancer to raise money for pancreatic research at Hopkins. Early visitors to the discussion board organized a major fundraising event, "Evening with the Stars", which raised over $100,000 to assist in starting a new laboratory at Hopkins. Now, a number of families, including the Rolfe, Zgonina and Monastra families, have organized fundraisers to benefit the pancreatic cancer reseacrh program here at Johns Hopkins. [more details]
What Your Donation Buys
One human gene contained within a cloning vector $10 Membranes for screening new genes $15 Reagents needed to isolate DNA from a patients' blood sample $20 A pair of PCR primers used to amplify one gene $30 Bacterial clone containing tumor-related gene $30 Vials for freezing tumor samples $35 Enzyme to precisely cut DNA $40 Scalpel blades for dissection of tumor samples $55 Enzyme to join DNA fragments $60 Updates to lab manual $70 Flasks for growing tumor cells $75 Radiolabel used to label DNA for sequencing and probing $100 Tumor cell line $100 Gel mix used to resolve DNA on gels $100 A vial of enzyme to modify or amplify DNA $100 Serum to grow cancer cells $130 DNA purification kit $150 Reagents to introduce genes into cancer cells $180 Purification kit for tumor-suppressor proteins $230 X-ray film to detect DNA sequence of a gene $270 Plates for drug-screening reactions $380 Enzyme to amplify DNA from tumors $400 DNA fragments to study a new gene $500 Lab refrigerator used in ongoing experiments $700 Digital camera for web page construction/updates $800 Set of pipettes to measure chemical solutions $900 Lab computer to access gene database $1,800 Ultraviolet light and camera to visualize DNA $2,000 Incubator for tumor cell culture $2,700 Set of DNA sequencing apparatus $3,800 Lab freezer $5,000 Centrifuge for drug screens and purifications $7,000 PCR machine to amplify DNA $9,000 Drier for DNA gels and purifications $12,000 Cancer Research Technician $30,000/yr Drug library to screen for new therapeutics (19,000 drugs) $38,000 Research fellow and supplies $50,000/yr Named endowment $100,000 and up Named endowed research fellowship $1.7 million Named endowed chair for pancreas cancer research $2.3 million Named endowed pancreas cancer center $10 million
The monies raised through this Web page are distributed under the direction of Dr. Ralph Hruban, are used primarily by our young faculty (Drs. Goggins and Iacobuzio-Donahue), and primarily support our research on the early detection of pancreatic cancer, the familial aggregation of pancreatic cancer, gene expression in pancreatic cancer, and for the development of mouse models of pancreatic cancer. Donations also support pilot projects, the purchase of cutting edge technology and research by our resident and fellow trainees.
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