CURRENT PROJECTS (refer to Publications Page)
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Naked DNA Vaccine
RNA Replicon Vaccine
RNA Replicon Particle Vaccine
Vaccinia Vaccine
Prime-Boost Strategies
Intracellular Targeting Strategies
Intercellular Spreading Strategies
Dendritic Cell Targeting Strategies
Combination of Immunotherapy and Anti-Angiogenesis
Prolongation of Dendritic Cell Life Using Antiapoptotic Proteins and RNA Interference
Identification of HPV-16 E6 and E7* Immunodominant Epitopes
E6 and E7 Gene Modification to Create Better DNA Vaccines
Combination of chemotherapy and immunotherapeutic strategies |
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*
E6 and E7 are consistently expressed in HPV-associated lesions and are responsible for malignant transformation of infected cells.